Prokaryotic versus eukaryotic genome structure, conservation (gene order/sequence/ structure, regulatory sequences), approaches to mapping/sequencing genomes, DNA sequencing, DNA sequencing technologies, approaches to genome annotation, SNPs, microarray technology, gene expression microarrays, antibodies, chromatin immuno¬purification, high throughput perturbation studies. Problem-solving/data-handling/critical thinking/journal-club sessions. Possible interactions with Genomics Research Core facility.