Samir Hamdan

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Research activity per year

Personal profile

Research Overview

Professor Hamdan's research interest is focused on the reconstitution, imaging and characterization of multi-protein nucleic acid binding machinaries at the single molecule level. Toward achieving this goal his lab uses an approach that combines conventional biochemical and biophysical tools with wide range of force and fluorescence single-molecule imaging techniques. The ability to observe enzymatic activities in real time at the single molecule level has profoundly changed how biochemical reactions are studied. By eliminating ensemble averaging, the distributions and fluctuations of molecular properties can be characterized, transient intermediates can be observed and identified, and catalytic mechanisms can be elucidated. Applying this multidisciplinary approach will provide a true molecular understanding of the mechanisms involved in replication, repair, and recombination. It will also extend the technique of single-molecule analysis from a few proteins to large multi-protein complexes, often containing many enzymatic activities.

Key Research Areas

Chemical Science

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 15 - Life on Land


Chemistry, Ph.D., Australian National University


Award Date: Jan 1 2002

Chemistry, M.S., Western Michigan University


Award Date: Jan 1 1998

Chemistry, B.S., Yarmouk University


Award Date: Jan 1 1995


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Collaborations and top research areas from the last five years

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