@inbook{66e5f823d377412ba8cba7fd543041f1,
title = "3D Multiscale Modelling of Angiogenesis and Vascular Tumour Growth",
abstract = "We present a three-dimensional, multiscale model of vascular tumour growth, which couples nutrient/growth factor transport, blood flow, angiogenesis, vascular remodelling, movement of and interactions between normal and tumour cells, and nutrient-dependent cell cycle dynamics within each cell. We present computational simulations which show how a vascular network may evolve and interact with tumour and healthy cells. We also demonstrate how our model may be combined with experimental data, to predict the spatio-temporal evolution of a vascular tumour.",
author = "H. Perfahl and Byrne, {H. M.} and T. Chen and V. Estrella and T. Alarc{\'o}n and A. Lapin and Gatenby, {R. A.} and Gillies, {R. J.} and Lloyd, {M. C.} and Maini, {P. K.} and M. Reuss and Owen, {M. R.}",
note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledged KAUST grant number(s): KUK-C1-1013-04 Acknowledgements: HMB, MRO and HP acknowledge financial support by the Marie CurieNetwork MMBNOTT (Project No. MEST-CT-2005-020723). RAG and PKM acknowledge partialsupport from NIH/NCI grant U54CA143970. HP, AL and MR thank the BMBF—FundingInitiative FORSYS Partner: “Predictive Cancer Therapy”. In vivo window chamber work wasfunded in part by Moffitt Cancer Center PS-OC NIH/NCI U54CA143970. This publication wasbased on work supported in part by Award No. KUK-C1-1013-04, made by King AbdullahUniversity of Science and Technology (KAUST). This publication acknowledges KAUST support, but has no KAUST affiliated authors.",
year = "2012",
month = nov,
day = "1",
doi = "10.1007/978-1-4614-4376-6_3",
language = "English (US)",
isbn = "9781461443759",
pages = "29--48",
booktitle = "Micro and Nano Flow Systems for Bioanalysis",
publisher = "Springer Nature",
}