A catalytic asymmetric electrocyclization-protonation reaction

Magnus Rueping*, Winai Ieawsuwan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

114 Scopus citations


The first enantioselective Brønsted acidcatalyzed electrocyclization-protonation reaction has been developed which provides a number of different cyclopentenones in good yields and with high enantioselectivities. The stereodetermining step of this asymmetric Nazarov cyclization reaction is an asymmetric Brønsted acid-catalyzed kinetic protonation.

Original languageEnglish (US)
Pages (from-to)78-84
Number of pages7
JournalAdvanced Synthesis and Catalysis
Issue number1-2
StatePublished - Jan 2009
Externally publishedYes


  • Brønsted acids
  • Cascade reaction
  • Cyclopentenone
  • Domino reaction
  • Nazarov reaction
  • Organic catalysis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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