A series of novel unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N- (aryl)acetamidines was synthesized by reacting ethyl(1E)-N-(4-oxo-2- phenylquinazolin-3(4H)-yl)ethanimidoate (2) and suitable reactive aromatic amines. Structures' determination of the synthesized compounds was carried out using spectroscopic techniques including IR, 1H NMR, and mass spectrometry. Structural effects on reactivity were also studied. © 2010 Rasool Khan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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