TY - GEN
T1 - A micro-pillar array to trap magnetic beads in microfluidic systems
AU - Gooneratne, Chinthaka Pasan
AU - Kosel, Jürgen
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2012/12
Y1 - 2012/12
N2 - A micro-pillar array (MPA) is proposed in this paper to trap and separate magnetic beads (MBs) in microfluidic systems. MBs are used in many biomedical applications due to being compatible in dimension to biomolecules, the large surface area available to attach biomolecules, and the fact that they can be controlled by a magnetic field. Trapping and separating these labeled biomolecules is an important step toward achieving reliable and accurate quantification for disease diagnostics. Nickel Iron (Ni50Fe 50) micro-pillars were fabricated on a Silicon (Si) substrate by standard microfabrication techniques. Experimental results showed that MBs could be trapped on the MPA at the single bead level and separated from other non-target particles. This principle can easily be extended to trap and separate target biomolecules in heterogeneous biological samples. © 2012 IEEE.
AB - A micro-pillar array (MPA) is proposed in this paper to trap and separate magnetic beads (MBs) in microfluidic systems. MBs are used in many biomedical applications due to being compatible in dimension to biomolecules, the large surface area available to attach biomolecules, and the fact that they can be controlled by a magnetic field. Trapping and separating these labeled biomolecules is an important step toward achieving reliable and accurate quantification for disease diagnostics. Nickel Iron (Ni50Fe 50) micro-pillars were fabricated on a Silicon (Si) substrate by standard microfabrication techniques. Experimental results showed that MBs could be trapped on the MPA at the single bead level and separated from other non-target particles. This principle can easily be extended to trap and separate target biomolecules in heterogeneous biological samples. © 2012 IEEE.
UR - http://hdl.handle.net/10754/564433
UR - http://ieeexplore.ieee.org/document/6461798/
UR - http://www.scopus.com/inward/record.url?scp=84874687644&partnerID=8YFLogxK
U2 - 10.1109/ICSensT.2012.6461798
DO - 10.1109/ICSensT.2012.6461798
M3 - Conference contribution
SN - 9781467322485
SP - 97
EP - 101
BT - 2012 Sixth International Conference on Sensing Technology (ICST)
PB - Institute of Electrical and Electronics Engineers (IEEE)
ER -