TY - JOUR
T1 - A note on tools for prediction under uncertainty and identifiability of SIR-like dynamical systems for epidemiology
AU - Piazzola, Chiara
AU - Tamellini, Lorenzo
AU - Tempone, Raul
N1 - KAUST Repository Item: Exported on 2020-11-24
Acknowledged KAUST grant number(s): URF/1/2584-01-01
Acknowledgements: The authors acknowledge the many fruitful discussions with several colleagues, and in particular the colleagues at CNR-IMATI that participated in the COVID-19 modeling study group.
PY - 2020/11
Y1 - 2020/11
N2 - We provide an overview of the methods that can be used for prediction under uncertainty and data fitting of dynamical systems, and of the fundamental challenges that arise in this context. The focus is on SIR-like models, that are being commonly used when attempting to predict the trend of the COVID-19 pandemic. In particular, we raise a warning flag about identifiability of the parameters of SIR-like models; often, it might be hard to infer the correct values of the parameters from data, even for very simple models, making it non-trivial to use these models for meaningful predictions. Most of the points that we touch upon are actually generally valid for inverse problems in more general setups.
AB - We provide an overview of the methods that can be used for prediction under uncertainty and data fitting of dynamical systems, and of the fundamental challenges that arise in this context. The focus is on SIR-like models, that are being commonly used when attempting to predict the trend of the COVID-19 pandemic. In particular, we raise a warning flag about identifiability of the parameters of SIR-like models; often, it might be hard to infer the correct values of the parameters from data, even for very simple models, making it non-trivial to use these models for meaningful predictions. Most of the points that we touch upon are actually generally valid for inverse problems in more general setups.
UR - http://hdl.handle.net/10754/664659
UR - https://linkinghub.elsevier.com/retrieve/pii/S0025556420301590
U2 - 10.1016/j.mbs.2020.108514
DO - 10.1016/j.mbs.2020.108514
M3 - Article
C2 - 33217409
SN - 0025-5564
SP - 108514
JO - Mathematical Biosciences
JF - Mathematical Biosciences
ER -