A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

Aansa Hanif; Aniqa Sardar; Meshari Alazmi; Haniya Tariq; Abdul-Hamid M. Emwas; Xin Gao; Ghayoor Abbas Chotana; Rahman Shah Zaib Saleem

doi:10.1002/slct.201803409

A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

Aansa Hanif, Aniqa Sardar, Meshari Alazmi, Haniya Tariq, Abdul-Hamid M. Emwas, Xin Gao, Ghayoor Abbas Chotana, Rahman Shah Zaib Saleem

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.

Original language	English (US)
Pages (from-to)	1753-1756
Number of pages	4
Journal	ChemistrySelect
Volume	4
Issue number	5
DOIs	https://doi.org/10.1002/slct.201803409
State	Published - Feb 5 2019

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10.1002/slct.201803409

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title = "A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives",

abstract = "A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.",

author = "Aansa Hanif and Aniqa Sardar and Meshari Alazmi and Haniya Tariq and Emwas, {Abdul-Hamid M.} and Xin Gao and Chotana, {Ghayoor Abbas} and Zaib Saleem, {Rahman Shah}",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Authors thank Lahore University of Management Sciences for support in the form of Faculty Initiative Fund and Higher Education Commission of Pakistan for the research grant. We also thank KAUST for the HRMS and X-ray crystal studies.",

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doi = "10.1002/slct.201803409",

language = "English (US)",

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T1 - A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

AU - Hanif, Aansa

AU - Sardar, Aniqa

AU - Alazmi, Meshari

AU - Tariq, Haniya

AU - Emwas, Abdul-Hamid M.

AU - Gao, Xin

AU - Chotana, Ghayoor Abbas

AU - Zaib Saleem, Rahman Shah

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Authors thank Lahore University of Management Sciences for support in the form of Faculty Initiative Fund and Higher Education Commission of Pakistan for the research grant. We also thank KAUST for the HRMS and X-ray crystal studies.

PY - 2019/2/5

Y1 - 2019/2/5

N2 - A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.

AB - A simple and convenient one-pot reaction for the synthesis of arylidene 2-aminoimidazolone derivatives from structurally diverse benzaldehydes, amines and 2-(methylthio)-1H-imidazol-4(5H)-one is described. The reaction offers flexibility of use of electron-rich and electron-deficient benzaldehydes and mono and di-substituted amines for the rapid development of combinatorial library.

UR - http://hdl.handle.net/10754/631668

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JO - ChemistrySelect

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A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

Abstract

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CCDC 1892401: Experimental Crystal Structure Determination : 5-[(4-hydroxyphenyl)methylidene]-2-(piperidin-1-yl)-1,5-dihydro-4H-imidazol-4-one

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A Novel One-Pot Three-Component Reaction for Rapid Access of Arylidene 2-Aminoimidazolone Derivatives

Abstract

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Datasets

CCDC 1892401: Experimental Crystal Structure Determination : 5-[(4-hydroxyphenyl)methylidene]-2-(piperidin-1-yl)-1,5-dihydro-4H-imidazol-4-one

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