A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces

G. Perozziello; G. Simone; M. Francardi; Rosanna La Rocca; N. Malara; P. Candeloro; E. Carbone; E. Di Fabrizio; A. Manz

A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces

G. Perozziello^*, G. Simone, M. Francardi, Rosanna La Rocca, N. Malara, P. Candeloro, E. Carbone, E. Di Fabrizio, A. Manz

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

In this study we propose a fast, simple method to biofunctionalize microfluidic systems for cellomic investigations based on microfluidic protocols. The combination of biofunctiolased surfaces and microfluidics gived the opportunity to create devices that can better diagnose disease, or discover cell functionalities. The developed systems can be used for different application in the cellomic fields In this work, they were tested to sort tumor cells and change tumor cell phenotypes. The results showed a high flexibility of the biofunctionalized protocols to create such systems in short time, with low reagent consumption and in a standard manner.

Original language	English (US)
Title of host publication	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages	1837-1839
Number of pages	3
Volume	3
State	Published - 2011
Externally published	Yes
Event	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States Duration: Oct 2 2011 → Oct 6 2011

Other

Other	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Country/Territory	United States
City	Seattle, WA
Period	10/2/11 → 10/6/11

Keywords

Biofunctionalization
Cell handling

ASJC Scopus subject areas

Control and Systems Engineering

Cite this

@inproceedings{4b866eb4e5374b408e2e08ca68415c81,

title = "A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces",

abstract = "In this study we propose a fast, simple method to biofunctionalize microfluidic systems for cellomic investigations based on microfluidic protocols. The combination of biofunctiolased surfaces and microfluidics gived the opportunity to create devices that can better diagnose disease, or discover cell functionalities. The developed systems can be used for different application in the cellomic fields In this work, they were tested to sort tumor cells and change tumor cell phenotypes. The results showed a high flexibility of the biofunctionalized protocols to create such systems in short time, with low reagent consumption and in a standard manner.",

keywords = "Biofunctionalization, Cell handling",

author = "G. Perozziello and G. Simone and M. Francardi and {La Rocca}, Rosanna and N. Malara and P. Candeloro and E. Carbone and {Di Fabrizio}, E. and A. Manz",

year = "2011",

language = "English (US)",

isbn = "9781618395955",

volume = "3",

pages = "1837--1839",

booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",

note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",

}

Perozziello, G, Simone, G, Francardi, M, La Rocca, R, Malara, N, Candeloro, P, Carbone, E, Di Fabrizio, E & Manz, A 2011, A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces. in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. vol. 3, pp. 1837-1839, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Seattle, WA, United States, 10/2/11.

A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces. / Perozziello, G.; Simone, G.; Francardi, M. et al.
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Vol. 3 2011. p. 1837-1839.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces

AU - Perozziello, G.

AU - Simone, G.

AU - Francardi, M.

AU - La Rocca, Rosanna

AU - Malara, N.

AU - Candeloro, P.

AU - Carbone, E.

AU - Di Fabrizio, E.

AU - Manz, A.

PY - 2011

Y1 - 2011

N2 - In this study we propose a fast, simple method to biofunctionalize microfluidic systems for cellomic investigations based on microfluidic protocols. The combination of biofunctiolased surfaces and microfluidics gived the opportunity to create devices that can better diagnose disease, or discover cell functionalities. The developed systems can be used for different application in the cellomic fields In this work, they were tested to sort tumor cells and change tumor cell phenotypes. The results showed a high flexibility of the biofunctionalized protocols to create such systems in short time, with low reagent consumption and in a standard manner.

AB - In this study we propose a fast, simple method to biofunctionalize microfluidic systems for cellomic investigations based on microfluidic protocols. The combination of biofunctiolased surfaces and microfluidics gived the opportunity to create devices that can better diagnose disease, or discover cell functionalities. The developed systems can be used for different application in the cellomic fields In this work, they were tested to sort tumor cells and change tumor cell phenotypes. The results showed a high flexibility of the biofunctionalized protocols to create such systems in short time, with low reagent consumption and in a standard manner.

KW - Biofunctionalization

KW - Cell handling

UR - http://www.scopus.com/inward/record.url?scp=84879801589&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84879801589

SN - 9781618395955

VL - 3

SP - 1837

EP - 1839

BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

Y2 - 2 October 2011 through 6 October 2011

ER -

A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces

Abstract

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Keywords

ASJC Scopus subject areas

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