TY - JOUR
T1 - Additive inheritance of histone modifications in Arabidopsis thaliana intra-specific hybrids
AU - Moghaddam, Ali M.Banaei
AU - Roudier, Francois
AU - Seifert, Michael
AU - Bérard, Caroline
AU - Magniette, Marie Laure M.
AU - Ashtiyani, Raheleh Karimi
AU - Houben, Andreas
AU - Colot, Vincent
AU - Mette, Michael F.
N1 - Funding Information:
Received 19 March 2001, accepted 30 August 2001. Supported by the NIH (AR20613, R01 AG12561). Address correspondence to: David Felson, MD, MPH, Boston University Arthritis Center, 715 Albany Street, A203, Boston, MA 02118. Tel: (617) 638-5180; Fax: (617) 638-5239; E-mail: [email protected]
PY - 2011/8
Y1 - 2011/8
N2 - Plant genomes are earmarked with defined patterns of chromatin marks. Little is known about the stability of these epigenomes when related, but distinct genomes are brought together by intra-species hybridization. Arabidopsis thaliana accessions and their reciprocal hybrids were used as a model system to investigate the dynamics of histone modification patterns. The genome-wide distribution of histone modifications H3K4me2 and H3K27me3 in the inbred parental accessions Col-0, C24 and Cvi and their hybrid offspring was compared by chromatin immunoprecipitation in combination with genome tiling array hybridization. The analysis revealed that, in addition to DNA sequence polymorphisms, chromatin modification variations exist among accessions of A. thaliana. The range of these variations was higher for H3K27me3 (typically a repressive mark) than for H3K4me2 (typically an active mark). H3K4me2 and H3K27me3 were rather stable in response to intra-species hybridization, with mainly additive inheritance in hybrid offspring. In conclusion, intra-species hybridization does not result in gross changes to chromatin modifications.
AB - Plant genomes are earmarked with defined patterns of chromatin marks. Little is known about the stability of these epigenomes when related, but distinct genomes are brought together by intra-species hybridization. Arabidopsis thaliana accessions and their reciprocal hybrids were used as a model system to investigate the dynamics of histone modification patterns. The genome-wide distribution of histone modifications H3K4me2 and H3K27me3 in the inbred parental accessions Col-0, C24 and Cvi and their hybrid offspring was compared by chromatin immunoprecipitation in combination with genome tiling array hybridization. The analysis revealed that, in addition to DNA sequence polymorphisms, chromatin modification variations exist among accessions of A. thaliana. The range of these variations was higher for H3K27me3 (typically a repressive mark) than for H3K4me2 (typically an active mark). H3K4me2 and H3K27me3 were rather stable in response to intra-species hybridization, with mainly additive inheritance in hybrid offspring. In conclusion, intra-species hybridization does not result in gross changes to chromatin modifications.
KW - Arabidopsis thaliana
KW - ChIP on chip
KW - epigenome
KW - heterosis
KW - histone methylation
KW - intra-specific hybrids
UR - http://www.scopus.com/inward/record.url?scp=80051663971&partnerID=8YFLogxK
U2 - 10.1111/j.1365-313X.2011.04628.x
DO - 10.1111/j.1365-313X.2011.04628.x
M3 - Article
C2 - 21554454
AN - SCOPUS:80051663971
SN - 0960-7412
VL - 67
SP - 691
EP - 700
JO - Plant Journal
JF - Plant Journal
IS - 4
ER -