Advances in pulmonary delivery of nanoparticles

Gunjeet Kaur, R. K. Narang, Goutam Rath, Amit K. Goyal

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Nanotechnology has potential in the development of novel and effective delivery of drugs within lungs. Different strategies have been utilized for pulmonary delivery of drugs, including the use of lipid-based delivery systems (liposomes, ISCOMs, SLNs), use of polymeric matrix (PLGA, poly caprolactone, cynoacrylates, gelatin), development of polysaccharide particulates (chitosan, alginates, Carbopol, etc.), biocompatible metallic inorganic particles (iron, gold, zinc), etc. This paper reviews various nanopaticulate approaches in the form of lipids, polymers, metals, polysaccharides, or emulsions based for pulmonary drug delivery that could provide an increased biological efficacy and better local and systemic action. © 2012 Informa Healthcare USA, Inc.
Original languageEnglish (US)
Pages (from-to)75-96
Number of pages22
JournalArtificial Cells, Blood Substitutes, and Biotechnology
Volume40
Issue number1-2
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biotechnology

Fingerprint

Dive into the research topics of 'Advances in pulmonary delivery of nanoparticles'. Together they form a unique fingerprint.

Cite this