(Chemical Equation Presented) The enantioselective Brønsted acid catalyzed addition of methyleneaminopyrrolidine to N-Boc imines has been achieved in the presence of chiral phosphoric acids derived from 3,3′-di(phenanthryl)-H8-BINOL. The corresponding aminohydrazones have been isolated in good yields with enantiomeric excesses up to 90%.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry