An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin

Cameron C. Lee, Andrew T. Cramer, Francis C. Szoka, Jean M.J. Fréchet*

*Corresponding author for this work

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Pharmacology, Toxicology and Pharmaceutical Science

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