TY - JOUR
T1 - An on-surface Diels–Alder reaction
AU - Castro-Esteban, Jesús
AU - Albrecht, Florian
AU - Fatayer, Shadi
AU - Pérez, Dolores
AU - Gross, Leo
AU - Peña, Diego
N1 - Generated from Scopus record by KAUST IRTS on 2022-09-13
PY - 2021/12/6
Y1 - 2021/12/6
N2 - The Diels–Alder reaction is one of the most popular reactions in organic chemistry. However, its use in the field of on-surface synthesis is hampered by the spatial restrictions of this cycloaddition reaction. Herein we selected a cyclic strained triyne to demonstrate an on-surface hexadehydro-Diels–Alder reaction in a single molecule. The reaction was studied in detail by means of atomic force microscopy (AFM) with CO-functionalized tips. Our results pave the way to use this iconic pericyclic reaction for on-surface synthesis, introducing the concept of atom economy in the field.
AB - The Diels–Alder reaction is one of the most popular reactions in organic chemistry. However, its use in the field of on-surface synthesis is hampered by the spatial restrictions of this cycloaddition reaction. Herein we selected a cyclic strained triyne to demonstrate an on-surface hexadehydro-Diels–Alder reaction in a single molecule. The reaction was studied in detail by means of atomic force microscopy (AFM) with CO-functionalized tips. Our results pave the way to use this iconic pericyclic reaction for on-surface synthesis, introducing the concept of atom economy in the field.
UR - https://onlinelibrary.wiley.com/doi/10.1002/anie.202110311
UR - http://www.scopus.com/inward/record.url?scp=85118759803&partnerID=8YFLogxK
U2 - 10.1002/anie.202110311
DO - 10.1002/anie.202110311
M3 - Article
C2 - 34664770
SN - 1521-3773
VL - 60
SP - 26346
EP - 26350
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 50
ER -