Anaerobicizing into pluripotency

Athanasia D. Panopoulos, Juan Carlos Izpisua Belmonte*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

23 Scopus citations


Reprogramming involves multiple layers of molecular regulation, yet it remains relatively unknown how the cell's metabolism is changing and/or contributing to this process. In this issue of Cell Metabolism, Folmes et al. (2011) demonstrate that reprogramming induces a bioenergetic transition from an oxidative to a glycolytic state, and provide evidence to suggest that these changes may precede pluripotency.

Original languageEnglish (US)
Pages (from-to)143-144
Number of pages2
JournalCell Metabolism
Issue number2
StatePublished - Aug 3 2011
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


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