Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry

Jeffrey W. Leon; Jean M.J. Fréchet

doi:10.1007/BF00297611

Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry

Jeffrey W. Leon^*, Jean M.J. Fréchet

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Polyether dendrimers with differing chain end functionalites and molecular topologies were analyzed by MALDI-TOF mass spectrometry. The success of this analytical method is highly dependent on the type of matrix and sample preparation used. Ester and perdeuterophenyl terminated dendrimers with molecular weights up to 14,000 amu were successfully analyzed using an indoleacrylic acid matrix in tetrahydrofuran. Hybrid block copolymers consisting of linear polystyrene or poly (ethylene glycol) chains attached to one or two dendrimers gave spectra with oligomeric resolution in matrices of t-retinoic acid and 2-nitrophenyl octyl ether respectively. The MALDI-TOF results provide access to molecular weight distribution data confirming the results of size exclusion chromatography (SEC) analysis.

Original language	English (US)
Pages (from-to)	449-455
Number of pages	7
Journal	Polymer Bulletin
Volume	35
Issue number	4
DOIs	https://doi.org/10.1007/BF00297611
State	Published - Oct 1995
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics
Polymers and Plastics
Materials Chemistry

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10.1007/BF00297611

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@article{2361f0b43ea34a29822e470663cf6aef,

title = "Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry",

abstract = "Polyether dendrimers with differing chain end functionalites and molecular topologies were analyzed by MALDI-TOF mass spectrometry. The success of this analytical method is highly dependent on the type of matrix and sample preparation used. Ester and perdeuterophenyl terminated dendrimers with molecular weights up to 14,000 amu were successfully analyzed using an indoleacrylic acid matrix in tetrahydrofuran. Hybrid block copolymers consisting of linear polystyrene or poly (ethylene glycol) chains attached to one or two dendrimers gave spectra with oligomeric resolution in matrices of t-retinoic acid and 2-nitrophenyl octyl ether respectively. The MALDI-TOF results provide access to molecular weight distribution data confirming the results of size exclusion chromatography (SEC) analysis.",

author = "Leon, {Jeffrey W.} and Fr{\'e}chet, {Jean M.J.}",

year = "1995",

month = oct,

doi = "10.1007/BF00297611",

language = "English (US)",

volume = "35",

pages = "449--455",

journal = "Polymer Bulletin",

issn = "0170-0839",

publisher = "Springer Verlag",

number = "4",

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TY - JOUR

T1 - Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry

AU - Leon, Jeffrey W.

AU - Fréchet, Jean M.J.

PY - 1995/10

Y1 - 1995/10

N2 - Polyether dendrimers with differing chain end functionalites and molecular topologies were analyzed by MALDI-TOF mass spectrometry. The success of this analytical method is highly dependent on the type of matrix and sample preparation used. Ester and perdeuterophenyl terminated dendrimers with molecular weights up to 14,000 amu were successfully analyzed using an indoleacrylic acid matrix in tetrahydrofuran. Hybrid block copolymers consisting of linear polystyrene or poly (ethylene glycol) chains attached to one or two dendrimers gave spectra with oligomeric resolution in matrices of t-retinoic acid and 2-nitrophenyl octyl ether respectively. The MALDI-TOF results provide access to molecular weight distribution data confirming the results of size exclusion chromatography (SEC) analysis.

AB - Polyether dendrimers with differing chain end functionalites and molecular topologies were analyzed by MALDI-TOF mass spectrometry. The success of this analytical method is highly dependent on the type of matrix and sample preparation used. Ester and perdeuterophenyl terminated dendrimers with molecular weights up to 14,000 amu were successfully analyzed using an indoleacrylic acid matrix in tetrahydrofuran. Hybrid block copolymers consisting of linear polystyrene or poly (ethylene glycol) chains attached to one or two dendrimers gave spectra with oligomeric resolution in matrices of t-retinoic acid and 2-nitrophenyl octyl ether respectively. The MALDI-TOF results provide access to molecular weight distribution data confirming the results of size exclusion chromatography (SEC) analysis.

UR - http://www.scopus.com/inward/record.url?scp=0000812797&partnerID=8YFLogxK

U2 - 10.1007/BF00297611

DO - 10.1007/BF00297611

M3 - Article

AN - SCOPUS:0000812797

SN - 0170-0839

VL - 35

SP - 449

EP - 455

JO - Polymer Bulletin

JF - Polymer Bulletin

IS - 4

ER -

Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry

Abstract

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