TY - JOUR
T1 - Applications of nanodiamonds in drug delivery and catalysis
AU - Moosa, Basem
AU - Fhayli, Karim
AU - Li, Song
AU - Julfakyan, Khachatur
AU - Ezzeddine, Alaa
AU - Khashab, Niveen M.
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: The authors gratefully acknowledge financial support from King Abdullah University of Science and Technology (KAUST).
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The interest of researchers in utilizing nanomaterials as carriers for a wide spectrum of molecules has exploded in the last two decades. Nanodiamonds are one class of carbon-based nanomaterials that have emerged as promising drug delivery vehicles and imaging probes. Their ease of functionalization also led to the generation of stimuli-responsive nanodiamonds that deliver drugs on demand in a controlled manner. The ample surface area of NDs allowed for a higher loading of not only small molecules but also macromolecules like genes and proteins. Recently, the unique surface of NDs has attracted more attention as catalyst support in a huge range of organic modification and C-C bond formation reactions. Herein, recent advances in the utilization of nanodiamonds as a drug delivery vehicle and catalytical support are highlighted and summarized to illustrate the potential and versatility of this cheap and commercially available nanomaterial. Copyright © 2014 American Scientific Publishers All rights reserved.
AB - The interest of researchers in utilizing nanomaterials as carriers for a wide spectrum of molecules has exploded in the last two decades. Nanodiamonds are one class of carbon-based nanomaterials that have emerged as promising drug delivery vehicles and imaging probes. Their ease of functionalization also led to the generation of stimuli-responsive nanodiamonds that deliver drugs on demand in a controlled manner. The ample surface area of NDs allowed for a higher loading of not only small molecules but also macromolecules like genes and proteins. Recently, the unique surface of NDs has attracted more attention as catalyst support in a huge range of organic modification and C-C bond formation reactions. Herein, recent advances in the utilization of nanodiamonds as a drug delivery vehicle and catalytical support are highlighted and summarized to illustrate the potential and versatility of this cheap and commercially available nanomaterial. Copyright © 2014 American Scientific Publishers All rights reserved.
UR - http://hdl.handle.net/10754/565956
UR - http://openurl.ingenta.com/content/xref?genre=article&issn=1533-4880&volume=14&issue=1&spage=332
UR - http://www.scopus.com/inward/record.url?scp=84893722149&partnerID=8YFLogxK
U2 - 10.1166/jnn.2014.9141
DO - 10.1166/jnn.2014.9141
M3 - Article
C2 - 24730266
SN - 1533-4880
VL - 14
SP - 332
EP - 343
JO - Journal of Nanoscience and Nanotechnology
JF - Journal of Nanoscience and Nanotechnology
IS - 1
ER -