TY - JOUR
T1 - Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3
AU - Li, Yuanyuan
AU - Cai, Huixian
AU - Liu, Pu
AU - Wang, Chunyan
AU - Gao, Huiyang
AU - Wu, Changai
AU - Yan, Kang
AU - Zhang, Shizhong
AU - Huang, Jinguang
AU - Zheng, Chengchao
N1 - KAUST Repository Item: Exported on 2022-06-03
Acknowledgements: We thank Dr. Heribert Hirt (Center for Desert Agriculture, King Abdullah University of Science and Technology) for kindly providing us the MAPKKK18pro
This publication acknowledges KAUST support, but has no KAUST affiliated authors.
PY - 2017/2/16
Y1 - 2017/2/16
N2 - Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.
AB - Mitogen-activated protein kinase (MAPK) cascades are conserved and vital signaling components in the responses to various ambient stresses. Here, we report the identification of MAPKKK18, a drought resistance associated MAPK kinase kinase in Arabidopsis. The mapkkk18 knockout mutants displayed hypersensitivity to drought stress, whereas overaccumulation of MAPKKK18 in transgenic Arabidopsis plants significantly enhanced the resistance to drought. Expression pattern analysis revealed that the inducible expression of MAPKKK18 by osmotic stress was ABA and the canonical ABA signaling pathway dependent. Furthermore, MAPKKK18 mainly exerted its regulatory roles via downstream MAPKK3. These findings uncovered important roles for MAPKKK18 in drought resistance and expanded our understanding of the MAPK pathways in modulating abiotic stress responses.
UR - http://hdl.handle.net/10754/678502
UR - https://linkinghub.elsevier.com/retrieve/pii/S0006291X17301638
UR - http://www.scopus.com/inward/record.url?scp=85010987098&partnerID=8YFLogxK
U2 - 10.1016/j.bbrc.2017.01.104
DO - 10.1016/j.bbrc.2017.01.104
M3 - Article
SN - 1090-2104
VL - 484
SP - 292
EP - 297
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -