Astrocytes couple synaptic activity to glucose utilization in the brain

Pierre J. Magistretti; Luc Pellerin

doi:10.1152/physiologyonline.1999.14.5.177

Astrocytes couple synaptic activity to glucose utilization in the brain

Pierre J. Magistretti^*, Luc Pellerin

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

213 Scopus citations

Abstract

Astrocytes have functional characteristics that make them particularly well suited to couple glutamate uptake from the synaptic cleft to Na⁺-K⁺-ATPase activation and glucose utilization. The changes in glucose metabolism associated with these processes may provide signals detected by positron emission tomography.

Original language	English (US)
Pages (from-to)	177-182
Number of pages	6
Journal	News in Physiological Sciences
Volume	14
Issue number	5
DOIs	https://doi.org/10.1152/physiologyonline.1999.14.5.177
State	Published - Oct 1999
Externally published	Yes

ASJC Scopus subject areas

Physiology

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10.1152/physiologyonline.1999.14.5.177

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title = "Astrocytes couple synaptic activity to glucose utilization in the brain",

abstract = "Astrocytes have functional characteristics that make them particularly well suited to couple glutamate uptake from the synaptic cleft to Na+-K+-ATPase activation and glucose utilization. The changes in glucose metabolism associated with these processes may provide signals detected by positron emission tomography.",

author = "Magistretti, {Pierre J.} and Luc Pellerin",

year = "1999",

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journal = "News in Physiological Sciences",

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AU - Pellerin, Luc

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AB - Astrocytes have functional characteristics that make them particularly well suited to couple glutamate uptake from the synaptic cleft to Na+-K+-ATPase activation and glucose utilization. The changes in glucose metabolism associated with these processes may provide signals detected by positron emission tomography.

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DO - 10.1152/physiologyonline.1999.14.5.177

M3 - Article

AN - SCOPUS:0033464868

SN - 0886-1714

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SP - 177

EP - 182

JO - News in Physiological Sciences

JF - News in Physiological Sciences

IS - 5

ER -

Astrocytes couple synaptic activity to glucose utilization in the brain

Abstract

ASJC Scopus subject areas

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