Asymmetric dimethylarginine, cortisol/cortisone ratio, and C-peptide: Markers for diabetes and cardiovascular risk?

Jeffrey L. Anderson, John F. Carlquist, William L. Roberts, Benjamin D. Horne, Heidi T. May, Elisabeth L. Schwarz, Marzia Pasquali, Rebecca Nielson, Mark M. Kushnir, Alan L. Rockwood, Tami L. Bair, Joseph B. Muhlestein

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Background: Diabetes and prediabetic conditions are growing cardiovascular risk factors. Better understanding and earlier recognition and treatment of dysglycemia-related risk are health priorities. We assessed the predictive value of 3 proposed new markers for diabetes and cardiovascular risk. We tested whether the plasma levels of (1) asymmetric dimethylarginine (ADMA), (2) cortisol/cortisone (Cl/Cn) ratio, and (3) C-peptide predicted glycemic status, coronary artery disease, and death or myocardial infarction (MI) in a nested case-control cohort (N = 850) with normal fasting glucose (
Original languageEnglish (US)
Pages (from-to)67-73
Number of pages7
JournalAmerican Heart Journal
Volume153
Issue number1
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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