Bioconjugated silicon quantum dots from one-step green synthesis

Romuald Intartaglia; Annette Barchanski; Komal Bagga; Alessandro Genovese; Gobind Das; Philipp Wagener; Enzo Di Fabrizio; Alberto Diaspro; Fernando Brandi; Stephan Barcikowski

doi:10.1039/c2nr11763k

Bioconjugated silicon quantum dots from one-step green synthesis

Romuald Intartaglia^*, Annette Barchanski, Komal Bagga, Alessandro Genovese, Gobind Das, Philipp Wagener, Enzo Di Fabrizio, Alberto Diaspro, Fernando Brandi, Stephan Barcikowski

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

Original language	English (US)
Pages (from-to)	1271-1274
Number of pages	4
Journal	Nanoscale
Volume	4
Issue number	4
DOIs	https://doi.org/10.1039/c2nr11763k
State	Published - Feb 21 2012
Externally published	Yes

ASJC Scopus subject areas

General Materials Science

Access to Document

10.1039/c2nr11763k

Cite this

@article{b149a95aee4444b9ad118a1f5f3397ce,

title = "Bioconjugated silicon quantum dots from one-step green synthesis",

abstract = "Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.",

author = "Romuald Intartaglia and Annette Barchanski and Komal Bagga and Alessandro Genovese and Gobind Das and Philipp Wagener and {Di Fabrizio}, Enzo and Alberto Diaspro and Fernando Brandi and Stephan Barcikowski",

year = "2012",

month = feb,

day = "21",

doi = "10.1039/c2nr11763k",

language = "English (US)",

volume = "4",

pages = "1271--1274",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

number = "4",

}

TY - JOUR

T1 - Bioconjugated silicon quantum dots from one-step green synthesis

AU - Intartaglia, Romuald

AU - Barchanski, Annette

AU - Bagga, Komal

AU - Genovese, Alessandro

AU - Das, Gobind

AU - Wagener, Philipp

AU - Di Fabrizio, Enzo

AU - Diaspro, Alberto

AU - Brandi, Fernando

AU - Barcikowski, Stephan

PY - 2012/2/21

Y1 - 2012/2/21

N2 - Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

AB - Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

UR - http://www.scopus.com/inward/record.url?scp=84857222798&partnerID=8YFLogxK

U2 - 10.1039/c2nr11763k

DO - 10.1039/c2nr11763k

M3 - Article

C2 - 22252263

AN - SCOPUS:84857222798

SN - 2040-3364

VL - 4

SP - 1271

EP - 1274

JO - Nanoscale

JF - Nanoscale

IS - 4

ER -

Bioconjugated silicon quantum dots from one-step green synthesis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this