Biomedical research in a digital health framework

Isaac Cano, Magí Lluch-Ariet, David Gomez-Cabrero, Dieter Maier, Susana Kalko, Marta Cascante, Jesper Tegnér, Felip Miralles, Diego Herrera, Josep Roca

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project. The DHF aims to embrace the emerging requirements -data and tools -of applying systems medicine into healthcare with a three-tier strategy articulating formal healthcare, informal care and biomedical research. Accordingly, it has been constructed based on three key building blocks, namely, novel integrated care services with the support of information and communication technologies, a personal health folder (PHF) and a biomedical research environment (DHF-research). Details on the functional requirements and necessary components of the DHF-research are extensively presented. Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed. The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.
Original languageEnglish (US)
JournalJournal of Translational Medicine
StatePublished - Nov 28 2014
Externally publishedYes


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