TY - JOUR
T1 - Brønsted Base Assisted Photoredox Catalysis: Proton Coupled Electron Transfer for Remote C−C Bond Formation via Amidyl Radicals
AU - Jia, Jiaqi
AU - Ho, Yee Ann
AU - Bülow, Raoul F.
AU - Rueping, Magnus
N1 - KAUST Repository Item: Exported on 2020-04-23
Acknowledgements: Y.A.H. would like to thank Deutscher Akademischer Austauschdienst (DAAD) for a doctoral scholarship. The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement no. 617044 (SunCatChem).
PY - 2018/8/27
Y1 - 2018/8/27
N2 - The synthesis of alkyne- and alkene-decorated lactams has been achieved through a photoredox-initiated radical cascade reaction. The developed Brønsted base assisted, photoredox-catalyzed, intramolecular 5-exo-trig cyclization/intermolecular radical addition/elimination reaction provides facile access to functionalized γ-lactams, with good functional group tolerance and high yields.
AB - The synthesis of alkyne- and alkene-decorated lactams has been achieved through a photoredox-initiated radical cascade reaction. The developed Brønsted base assisted, photoredox-catalyzed, intramolecular 5-exo-trig cyclization/intermolecular radical addition/elimination reaction provides facile access to functionalized γ-lactams, with good functional group tolerance and high yields.
UR - http://hdl.handle.net/10754/628808
UR - https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201802907
UR - http://www.scopus.com/inward/record.url?scp=85052758008&partnerID=8YFLogxK
U2 - 10.1002/chem.201802907
DO - 10.1002/chem.201802907
M3 - Article
C2 - 29939456
AN - SCOPUS:85052758008
SN - 0947-6539
VL - 24
SP - 14054
EP - 14058
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
IS - 53
ER -