TY - JOUR
T1 - Brain Waves Spectral Analysis of Human Responses to Odorous and Non-Odorous Substances: A Preliminary Study.
AU - Chow, Xiao Hong
AU - Ting, Chee-Ming
AU - Wan Hamizan, Aneeza Khairiyah
AU - Zahedi, Farah Dayana
AU - Tan, Hui Jan
AU - Remli, Rabani
AU - Khoo, Ching Soong
AU - Ombao, Hernando
AU - Sahibulddin, Siti Zaleha
AU - Husain, Salina
N1 - KAUST Repository Item: Exported on 2023-06-05
Acknowledgements: This research was supported by Universiti Kebangsaan Malaysia Medical Center. A financial research grant was provided by the Universiti Kebangsaan Malaysia Medical Center (Project code: AZ19-76). The authors would like to thank Tan Lee Hui and Evelyn Tan Hui Ru, who contributed to the EEG spectral analysis. We would also like to gratefully acknowledge the volunteers for their participations in the study.
PY - 2023/6/1
Y1 - 2023/6/1
N2 - Objective: The aim of this study is to identify the potential electrophysiological biomarkers of human responses by comparing the electroencephalogram (EEG) brain wave changes toward lavender versus normal saline in a healthy human population.
Methods: This study included a total of 44 subjects without subjective olfactory disturbances. Lavender and normal saline were used as the olfactory stimulant and control. EEG was recorded and power spectra were analysed by the spectral analysis for each alpha, beta, delta, theta and gamma bandwidth frequency upon exposure to lavender and normal saline independently.
Results: The oscillatory brain activities in response to the olfactory stimulant indicated that the lavender smell decreased the beta activity in the left frontal (F7 electrode) and central region (C3 electrode) with a reduction in the gamma activity in the right parietal region (P4 electrode) (p < 0.05).
Conclusion: Olfactory stimulants result in the changes of the electrical brain activities at different brain regions, as evidenced by the topographical brain map and spectra analysis of each brain wave.
AB - Objective: The aim of this study is to identify the potential electrophysiological biomarkers of human responses by comparing the electroencephalogram (EEG) brain wave changes toward lavender versus normal saline in a healthy human population.
Methods: This study included a total of 44 subjects without subjective olfactory disturbances. Lavender and normal saline were used as the olfactory stimulant and control. EEG was recorded and power spectra were analysed by the spectral analysis for each alpha, beta, delta, theta and gamma bandwidth frequency upon exposure to lavender and normal saline independently.
Results: The oscillatory brain activities in response to the olfactory stimulant indicated that the lavender smell decreased the beta activity in the left frontal (F7 electrode) and central region (C3 electrode) with a reduction in the gamma activity in the right parietal region (P4 electrode) (p < 0.05).
Conclusion: Olfactory stimulants result in the changes of the electrical brain activities at different brain regions, as evidenced by the topographical brain map and spectra analysis of each brain wave.
UR - http://hdl.handle.net/10754/692340
UR - https://www.cambridge.org/core/product/identifier/S0022215123000919/type/journal_article
U2 - 10.1017/s0022215123000919
DO - 10.1017/s0022215123000919
M3 - Article
C2 - 37259908
SN - 0022-2151
SP - 1
EP - 26
JO - The Journal of laryngology and otology
JF - The Journal of laryngology and otology
ER -
