Cascade Cross-Coupling of Dienes: Photoredox and Nickel Dual Catalysis

Long Huang, Chen Zhu, Liang Yi, Huifeng Yue, Rajesh Kancherla, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Chemical transformations based on cascade reactions have the potential to simplify the preparation of diverse and architecturally complex molecules dramatically. Herein, we disclose an unprecedented and efficient method for the cross-coupling of radical precursors, dienes, and electrophilic coupling partners via a photoredox- and nickel-enabled cascade cross-coupling process. The cascade reaction furnishes a diverse array of saturated carbo- and heterocyclic scaffolds, thus providing access to a quick gain in C−C bond saturation
Original languageEnglish (US)
Pages (from-to)465-472
Number of pages8
JournalAngewandte Chemie
Issue number1
StatePublished - Nov 28 2019


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