Catalytic asymmetric domino Michael-Henry reaction: Enantioselective access to bicycles with consecutive quaternary ceuters by using bifunctional catalysts

Magnus Rueping; Alexander Kuenkel; Roland Fröhlich

doi:10.1002/chem.201000237

Catalytic asymmetric domino Michael-Henry reaction: Enantioselective access to bicycles with consecutive quaternary ceuters by using bifunctional catalysts

Magnus Rueping^*, Alexander Kuenkel, Roland Fröhlich

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

"Chemical Equotion Presentation" Domino catalysis: Two consecutive quaternary stereocenters, three functional groups, and four stereogenic centers have been created in the newly developed domino Michael-Henry reaction (see scheme) employing small amounts of a bifunctional organocatalyst.

Original language	English (US)
Pages (from-to)	4173-4176
Number of pages	4
Journal	Chemistry - A European Journal
Volume	16
Issue number	14
DOIs	https://doi.org/10.1002/chem.201000237
State	Published - Apr 12 2010
Externally published	Yes

Keywords

Cascade reactions
Domino reactions
Hydrogen bonds
Organocatalysis
Thioureas

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1002/chem.201000237

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title = "Catalytic asymmetric domino Michael-Henry reaction: Enantioselective access to bicycles with consecutive quaternary ceuters by using bifunctional catalysts",

abstract = "{"}Chemical Equotion Presentation{"} Domino catalysis: Two consecutive quaternary stereocenters, three functional groups, and four stereogenic centers have been created in the newly developed domino Michael-Henry reaction (see scheme) employing small amounts of a bifunctional organocatalyst.",

keywords = "Cascade reactions, Domino reactions, Hydrogen bonds, Organocatalysis, Thioureas",

author = "Magnus Rueping and Alexander Kuenkel and Roland Fr{\"o}hlich",

year = "2010",

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day = "12",

doi = "10.1002/chem.201000237",

language = "English (US)",

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pages = "4173--4176",

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T2 - Enantioselective access to bicycles with consecutive quaternary ceuters by using bifunctional catalysts

AU - Rueping, Magnus

AU - Kuenkel, Alexander

AU - Fröhlich, Roland

PY - 2010/4/12

Y1 - 2010/4/12

N2 - "Chemical Equotion Presentation" Domino catalysis: Two consecutive quaternary stereocenters, three functional groups, and four stereogenic centers have been created in the newly developed domino Michael-Henry reaction (see scheme) employing small amounts of a bifunctional organocatalyst.

AB - "Chemical Equotion Presentation" Domino catalysis: Two consecutive quaternary stereocenters, three functional groups, and four stereogenic centers have been created in the newly developed domino Michael-Henry reaction (see scheme) employing small amounts of a bifunctional organocatalyst.

KW - Cascade reactions

KW - Domino reactions

KW - Hydrogen bonds

KW - Organocatalysis

KW - Thioureas

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U2 - 10.1002/chem.201000237

DO - 10.1002/chem.201000237

M3 - Article

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SN - 0947-6539

VL - 16

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JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

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Catalytic asymmetric domino Michael-Henry reaction: Enantioselective access to bicycles with consecutive quaternary ceuters by using bifunctional catalysts

Abstract

Keywords

ASJC Scopus subject areas

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