Catalytic Wacker-type Oxidations Using Visible Light Photoredox Catalysis

Yee Ann Ho, Eva Paffenholz, Hyun Jin Kim, Benjamin Orgis, Magnus Rueping, David C. Fabry

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

A combined palladium/photoredox catalytic system for the efficient oxidation of terminal olefins to the corresponding methyl ketones is presented. The interplay of air, water, and light leads to a protocol in which the stoichiometric oxidants required for oxidative palladium catalysis are substituted with catalytic, single-electron transfer processes. Detailed mechanistic investigations revealed the role of the key components, in situ generated species, and catalysts. A broad range of substrates was examined in homogeneous as well as heterogeneous photoredox protocols, delivering the desired products in good yields.
Original languageEnglish (US)
Pages (from-to)1889-1892
Number of pages4
JournalChemCatChem
Volume11
Issue number7
DOIs
StatePublished - Mar 12 2019

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