@article{754c265113bc45118792763c26c5bec1,
title = "Cesium Carbonate-Catalyzed Synthesis of Phosphorothioates via S‑Phosphination of Thioketones",
abstract = "A highly efficient and environmentally-friendly base-mediated transition metal-free direct thiophlic catalytic approach has been reported for the synthesis of S-benzhydryl-phosphorothioates by reacting phosphite nucleophiles with diarylmethanethione. A wide variety of thioketones were coupled with different phosphite derivatives to provide the corresponding phosphorothioates in good to excellent yields. The control experiments, and density functional theory (DFT) calculations relies on the regio-selective thiophilic addition of phosphite nucleophile via umpolung protocols.",
author = "Ze-Wei Chen and Annamalai Pratheepkumar and Rekha Bai and Yongyi Hu and Badsara, {Satpal Singh} and Kuo-Wei Huang and Chin-Fa Lee",
note = "KAUST Repository Item: Exported on 2022-09-14 Acknowledgements: This work was financially supported by the Ministry of Science and Technology, Taiwan (Most 110-2113-M-005-014-MY3), National Chung Hsing University, i-Center for Advanced Science and Technology (iCAST), the “Innovation and Development Centre of Sustainable Agriculture (IDCSA)” from The Featured Areas Research Centre Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan and Science and Engineering Research Board-Department of Science. We are also grateful to the service of NOOR 2, Shaheen 2 High Performance Computing Facilities, and financial support from King Abdullah University of Science and Technology (KAUST).",
year = "2022",
month = sep,
day = "2",
doi = "10.1039/d2cc04331a",
language = "English (US)",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "ROYAL SOC CHEMISTRY",
}