Chip electrochromatography

Timothy B. Stachowiak, Frantisek Svec*, Jean M J Fréchet

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

99 Scopus citations


Electrochromatography (EC) in microfluidic chips is emerging as an attractive alternative to capillary electrophoresis (CE) for on-chip separations. This review summarizes recent developments in the rapidly growing area of chip electrochromatography with a focus on "column" technologies. Relevant achievements are summarized according to the types of stationary phase used for the separations including open channels, microfabricated structures, and channels packed with beads or containing a porous monolith. The advantages and disadvantages of each, as well as practical aspects of their application, are discussed. The analytical performance of these devices is demonstrated with separations involving various families of compounds mostly in the reversed-phase chromatographic mode.

Original languageEnglish (US)
Pages (from-to)97-111
Number of pages15
JournalJournal of Chromatography A
Issue number1-2
StatePublished - Jul 30 2004
Externally publishedYes


  • Chip technology
  • Electrochromatography
  • Reviews
  • Stationary phase, electrochromatography

ASJC Scopus subject areas

  • Analytical Chemistry


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