Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

Fei Wang; Wei Zhang; Jieming Zhu; Huaifeng Li; Kuo-Wei Huang; Jinbo Hu

doi:10.1039/c0cc04548a

Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

Fei Wang, Wei Zhang, Jieming Zhu, Huaifeng Li, Kuo-Wei Huang, Jinbo Hu

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131 Scopus citations

Abstract

A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.

Original language	English (US)
Pages (from-to)	2411-2413
Number of pages	3
Journal	Chem. Commun.
Volume	47
Issue number	8
DOIs	https://doi.org/10.1039/c0cc04548a
State	Published - 2011

ASJC Scopus subject areas

Materials Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Ceramics and Composites
General Chemistry
Catalysis
Electronic, Optical and Magnetic Materials

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title = "Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes",

abstract = "A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. {\textcopyright} 2011 The Royal Society of Chemistry.",

author = "Fei Wang and Wei Zhang and Jieming Zhu and Huaifeng Li and Kuo-Wei Huang and Jinbo Hu",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was supported by CAS and NFSC (20772144, 20825209, 20832008) to J.H. and by a KAUST baseline funding to K.-W.H.",

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doi = "10.1039/c0cc04548a",

language = "English (US)",

volume = "47",

pages = "2411--2413",

journal = "Chem. Commun.",

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T1 - Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

AU - Wang, Fei

AU - Zhang, Wei

AU - Zhu, Jieming

AU - Li, Huaifeng

AU - Huang, Kuo-Wei

AU - Hu, Jinbo

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was supported by CAS and NFSC (20772144, 20825209, 20832008) to J.H. and by a KAUST baseline funding to K.-W.H.

PY - 2011

Y1 - 2011

N2 - A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.

AB - A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.

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DO - 10.1039/c0cc04548a

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SN - 1359-7345

VL - 47

SP - 2411

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JO - Chem. Commun.

JF - Chem. Commun.

IS - 8

ER -

Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

Abstract

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