TY - JOUR
T1 - Comparison of Artemisia annua bioactivities between traditional medicine and chemical extracts
AU - Nageeb, Ahmed
AU - Altawashi, Azza
AU - Emwas, Abdul-Hamid M.
AU - Al-Talla, Zeyad
AU - Al Rifai, Nahla
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2014/4/4
Y1 - 2014/4/4
N2 - The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities. - See more at: http://www.eurekaselect.com/121416/article#sthash.2c2j9AoL.dpuf
AB - The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities. - See more at: http://www.eurekaselect.com/121416/article#sthash.2c2j9AoL.dpuf
UR - http://hdl.handle.net/10754/563488
UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992861
U2 - 10.2174/157340720904140404151439
DO - 10.2174/157340720904140404151439
M3 - Article
C2 - 24761137
SN - 1573-4072
VL - 9
SP - 324
EP - 332
JO - Current Bioactive Compounds
JF - Current Bioactive Compounds
IS - 4
ER -