Convergent catalysis: Asymmetric synthesis of dihydroquinolines using a combined metal catalysis and organocatalysis approach

Magnus Rueping; Jeremy Dufour; Lan Bui

doi:10.1021/cs401176s

Convergent catalysis: Asymmetric synthesis of dihydroquinolines using a combined metal catalysis and organocatalysis approach

Magnus Rueping^*, Jeremy Dufour, Lan Bui

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A convergent catalysis approach has been developed. The combined metal-catalyzed and organocatalyzed cascade consists of two oxidations, an aza-Michael addition and an aldol condensation, and involves a multicatalysis approach to provide 1,2-dihydroquinolines in a highly enantioselective fashion.

Original language	English (US)
Pages (from-to)	1021-1025
Number of pages	5
Journal	ACS Catalysis
Volume	4
Issue number	3
DOIs	https://doi.org/10.1021/cs401176s
State	Published - Mar 7 2014
Externally published	Yes

Keywords

Michael reaction
TPAP oxidation
aldol reaction
diphenylprolinol ether
domino reaction

ASJC Scopus subject areas

General Chemistry
Catalysis

Access to Document

10.1021/cs401176s

Cite this

@article{b8274e3a402e4b689afa3cc4acca5085,

title = "Convergent catalysis: Asymmetric synthesis of dihydroquinolines using a combined metal catalysis and organocatalysis approach",

abstract = "A convergent catalysis approach has been developed. The combined metal-catalyzed and organocatalyzed cascade consists of two oxidations, an aza-Michael addition and an aldol condensation, and involves a multicatalysis approach to provide 1,2-dihydroquinolines in a highly enantioselective fashion.",

keywords = "Michael reaction, TPAP oxidation, aldol reaction, diphenylprolinol ether, domino reaction",

author = "Magnus Rueping and Jeremy Dufour and Lan Bui",

year = "2014",

month = mar,

day = "7",

doi = "10.1021/cs401176s",

language = "English (US)",

volume = "4",

pages = "1021--1025",

journal = "ACS Catalysis",

issn = "2155-5435",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - Convergent catalysis

T2 - Asymmetric synthesis of dihydroquinolines using a combined metal catalysis and organocatalysis approach

AU - Rueping, Magnus

AU - Dufour, Jeremy

AU - Bui, Lan

PY - 2014/3/7

Y1 - 2014/3/7

N2 - A convergent catalysis approach has been developed. The combined metal-catalyzed and organocatalyzed cascade consists of two oxidations, an aza-Michael addition and an aldol condensation, and involves a multicatalysis approach to provide 1,2-dihydroquinolines in a highly enantioselective fashion.

AB - A convergent catalysis approach has been developed. The combined metal-catalyzed and organocatalyzed cascade consists of two oxidations, an aza-Michael addition and an aldol condensation, and involves a multicatalysis approach to provide 1,2-dihydroquinolines in a highly enantioselective fashion.

KW - Michael reaction

KW - TPAP oxidation

KW - aldol reaction

KW - diphenylprolinol ether

KW - domino reaction

UR - http://www.scopus.com/inward/record.url?scp=84896763365&partnerID=8YFLogxK

U2 - 10.1021/cs401176s

DO - 10.1021/cs401176s

M3 - Article

AN - SCOPUS:84896763365

SN - 2155-5435

VL - 4

SP - 1021

EP - 1025

JO - ACS Catalysis

JF - ACS Catalysis

IS - 3

ER -

Convergent catalysis: Asymmetric synthesis of dihydroquinolines using a combined metal catalysis and organocatalysis approach

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this