TY - JOUR
T1 - CovMT: an interactive SARS-CoV-2 mutation tracker, with a focus on critical variants.
AU - Alam, Intikhab
AU - Radovanovic, Aleksandar
AU - Incitti, Roberto
AU - Kamau, Allan A
AU - Alarawi, Mohammed
AU - Azhar, Esam I
AU - Gojobori, Takashi
N1 - KAUST Repository Item: Exported on 2021-02-15
PY - 2021/2/11
Y1 - 2021/2/11
N2 - The number of confirmed SARS-CoV-2 cases worldwide has now reached around 100 million, with 2·1 million reported deaths1 and more than 450 000 SARS-CoV-2 genomes already sequenced. It is vital to keep track of mutations in the genome of SARS-CoV-2, especially in the spike protein's receptor binding domain (RBD) region, which could potentially impact disease severity and treatment strategies.2, 3, 4 In the wake of a recent increase in cases with a more infective variant featuring an RBD mutation (N501Y, B.1.1.7) in the UK, countries worldwide are concerned about the spread of this or similar variants. Increasing sequencing efforts and user-friendly mutation tracking systems are needed for timely tracking of SARS-CoV-2 variants.
AB - The number of confirmed SARS-CoV-2 cases worldwide has now reached around 100 million, with 2·1 million reported deaths1 and more than 450 000 SARS-CoV-2 genomes already sequenced. It is vital to keep track of mutations in the genome of SARS-CoV-2, especially in the spike protein's receptor binding domain (RBD) region, which could potentially impact disease severity and treatment strategies.2, 3, 4 In the wake of a recent increase in cases with a more infective variant featuring an RBD mutation (N501Y, B.1.1.7) in the UK, countries worldwide are concerned about the spread of this or similar variants. Increasing sequencing efforts and user-friendly mutation tracking systems are needed for timely tracking of SARS-CoV-2 variants.
UR - http://hdl.handle.net/10754/667376
UR - https://linkinghub.elsevier.com/retrieve/pii/S1473309921000785
U2 - 10.1016/s1473-3099(21)00078-5
DO - 10.1016/s1473-3099(21)00078-5
M3 - Article
C2 - 33571446
SN - 1473-3099
JO - The Lancet. Infectious diseases
JF - The Lancet. Infectious diseases
ER -