TY - JOUR
T1 - CRISPR/Cas13 as a Tool for RNA Interference
AU - Ali, Zahir
AU - Mahas, Ahmed
AU - Mahfouz, Magdy M.
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): OSR-2015-CRG4-2647
Acknowledgements: We wish to thank the Office of Sponsored Research (OSR) and King Abdullah University of Science and Technology (KAUST) for their support (award OSR-2015-CRG4-2647).
PY - 2018/3/28
Y1 - 2018/3/28
N2 - Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.
AB - Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.
UR - http://hdl.handle.net/10754/627624
UR - http://www.sciencedirect.com/science/article/pii/S1360138518300451
UR - http://www.scopus.com/inward/record.url?scp=85044536756&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2018.03.003
DO - 10.1016/j.tplants.2018.03.003
M3 - Article
C2 - 29605099
SN - 1360-1385
VL - 23
SP - 374
EP - 378
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 5
ER -