Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition

Piotr Stefanowicz; Łukasz Jaremko; Mariusz Jaremko; Tadeusz Lis

doi:10.1039/b513741a

Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition

Piotr Stefanowicz, Łukasz Jaremko^*, Mariusz Jaremko, Tadeusz Lis

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.

Original language	English (US)
Pages (from-to)	258-265
Number of pages	8
Journal	New Journal of Chemistry
Volume	30
Issue number	2
DOIs	https://doi.org/10.1039/b513741a
State	Published - 2006
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Materials Chemistry

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title = "Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition",

abstract = "A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.",

author = "Piotr Stefanowicz and {\L}ukasz Jaremko and Mariusz Jaremko and Tadeusz Lis",

year = "2006",

doi = "10.1039/b513741a",

language = "English (US)",

volume = "30",

pages = "258--265",

journal = "New Journal of Chemistry",

issn = "1144-0546",

publisher = "Royal Society of Chemistry",

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T1 - Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition

AU - Stefanowicz, Piotr

AU - Jaremko, Łukasz

AU - Jaremko, Mariusz

AU - Lis, Tadeusz

PY - 2006

Y1 - 2006

N2 - A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.

AB - A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.

UR - http://www.scopus.com/inward/record.url?scp=32544432221&partnerID=8YFLogxK

U2 - 10.1039/b513741a

DO - 10.1039/b513741a

M3 - Article

AN - SCOPUS:32544432221

SN - 1144-0546

VL - 30

SP - 258

EP - 265

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 2

ER -

Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition

Abstract

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