Determination of folic acid using graphene/molybdenum disulfide nanosheets/gold nanoparticles ternary composite

Veerappan Mani, Mani Govindasamy, Shen Ming Chen, Boopathi Subramani, Anandaraj Sathiyan, Johnson Princy Merlin

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


Currently, graphene nanosheets (GNS) and molybdenum disulfide (MoS2) are two most popular 2D layered materials in electrochemical applications due to their excellent physico-chemical properties. Herein, we have developed a facile method to prepare a ternary nanocomposite composed of graphene, (MoS2and gold nanoparticles (AuNPs) and described its electrochemical sensing applicability in the determination of folic acid (FA). The morphological, elemental, impedance and electrochemical attributes of the GNS-MoS2-AuNPs ternary nanocomposite are studied in detail. Next, GNS-MoS2-AuNPs is deposited on screen printed electrode (SPCE) and applied for the electrochemical sensing of folic acid. Interestingly, the composite has excellent electrocatalytic ability to folic acid due to good synergic effect between GNS, MoS2 and AuNPs. The developed sensor detects FA in wide linear range of 50 nM-1150 μM and displays low detection limit of 38.5 nM. The sensor performance of the GNS-MoS2-AuNPs is either superior or comparable to the previously reported electrodes. Moreover, the electrode has good repeatability, reproducibility and stability. The practical applicability of the electrode is demonstrated in human urine samples and the results have shown good recovery.
Original languageEnglish (US)
Pages (from-to)258-267
Number of pages10
JournalInternational Journal of Electrochemical Science
Issue number1
StatePublished - Jan 1 2017
Externally publishedYes

ASJC Scopus subject areas

  • Electrochemistry


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