Abstract
A device for obtaining three-dimensional cell cultures comprises: a substrate (1); and a plurality of micro-structures (2) which protrude from the surface of the substrate (1) and are arranged on such substrate (1) according to a periodical grid so as to make the substrate (1) super hydrophobic. The device is characterized in that the micro-structures (2) have side walls at least partially nano-patterned and have projections (14) and recesses (16) alternated with a predetd. distance. Each micro-structure (2) comprises a silicon core, a biocompatible coating, and possibly an adhesion layer for said biocompatible coating, applied to the surface of the substrate. A method for producing the device is also presented. [on SciFinder(R)]
Original language | English (US) |
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Patent number | WO2013156941A1 |
State | Published - Oct 24 2013 |
Externally published | Yes |
Keywords
- super hydrophobic microstructure device three dime