Dissecting the plant chromatin interactome using mass spectrometry

Yanmei Chen*, Jun Xiao, Peng Liu

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


The protein interactome mediates crucial functions in transcription, chromatin remodeling, and higher-order structural organization. Elucidating the proteins that interact with chromatin-associated RNA or proteins is key to understanding fundamental epigenetic regulatory pathways. We discuss the opportunities and challenges of mass spectrometry (MS)-based proteomics for characterizing the plant chromatin interactome.

Original languageEnglish (US)
Pages (from-to)261-265
Number of pages5
JournalTrends in biotechnology
Issue number3
StatePublished - Mar 2022


  • chromatin
  • epigenetics
  • interactome
  • proteomics
  • RNA-binding protein

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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