Distributed Cerebral Blood Flow estimation using a spatiotemporal hemodynamic response model and a Kalman-like Filter approach

Zehor Belkhatir, Sarra Mechhoud, Taous-Meriem Laleg-Kirati

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

This paper discusses the estimation of distributed Cerebral Blood Flow (CBF) using spatiotemporal traveling wave model. We consider a damped wave partial differential equation that describes a physiological relationship between the blood mass density and the CBF. The spatiotemporal model is reduced to a finite dimensional system using a cubic b-spline continuous Galerkin method. A Kalman Filter with Unknown Inputs without Direct Feedthrough (KF-UI-WDF) is applied on the obtained reduced differential model to estimate the source term which is the CBF scaled by a factor. Numerical results showing the performances of the adopted estimator are provided.
Original languageEnglish (US)
Title of host publication2015 European Control Conference (ECC)
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages1349-1354
Number of pages6
ISBN (Print)9783952426937
DOIs
StatePublished - Nov 23 2015

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