DNA sensing by field-effect transistors based on networks of carbon nanotubes

Ling Gui Ee; Lain Jong Li; Keke Zhang; Yangping Xu; Xiaochen Dong; Xinning Ho; See Lee Pooi; Johnson Kasim; Z. X. Shen; John A. Rogers; S. G. Mhaisalkar

doi:10.1021/ja075176g

DNA sensing by field-effect transistors based on networks of carbon nanotubes

Ling Gui Ee, Lain Jong Li^*, Keke Zhang, Yangping Xu, Xiaochen Dong, Xinning Ho, See Lee Pooi, Johnson Kasim, Z. X. Shen, John A. Rogers, S. G. Mhaisalkar

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

141 Scopus citations

Abstract

We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

Original language	English (US)
Pages (from-to)	14427-14432
Number of pages	6
Journal	Journal of the American Chemical Society
Volume	129
Issue number	46
DOIs	https://doi.org/10.1021/ja075176g
State	Published - Nov 21 2007
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja075176g

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title = "DNA sensing by field-effect transistors based on networks of carbon nanotubes",

abstract = "We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.",

author = "Ee, {Ling Gui} and Li, {Lain Jong} and Keke Zhang and Yangping Xu and Xiaochen Dong and Xinning Ho and Pooi, {See Lee} and Johnson Kasim and Shen, {Z. X.} and Rogers, {John A.} and Mhaisalkar, {S. G.}",

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T1 - DNA sensing by field-effect transistors based on networks of carbon nanotubes

AU - Ee, Ling Gui

AU - Li, Lain Jong

AU - Zhang, Keke

AU - Xu, Yangping

AU - Dong, Xiaochen

AU - Ho, Xinning

AU - Pooi, See Lee

AU - Kasim, Johnson

AU - Shen, Z. X.

AU - Rogers, John A.

AU - Mhaisalkar, S. G.

PY - 2007/11/21

Y1 - 2007/11/21

N2 - We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

AB - We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

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U2 - 10.1021/ja075176g

DO - 10.1021/ja075176g

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AN - SCOPUS:36448953512

SN - 0002-7863

VL - 129

SP - 14427

EP - 14432

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 46

ER -

DNA sensing by field-effect transistors based on networks of carbon nanotubes

Abstract

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