DNA sensing by field-effect transistors based on networks of carbon nanotubes

Ling Gui Ee, Lain-Jong Li*, Keke Zhang, Yangping Xu, Xiaochen Dong, Xinning Ho, See Lee Pooi, Johnson Kasim, Z. X. Shen, John A. Rogers, S. G. Mhaisalkar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

140 Scopus citations


We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.

Original languageEnglish (US)
Pages (from-to)14427-14432
Number of pages6
JournalJournal of the American Chemical Society
Issue number46
StatePublished - Nov 21 2007

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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