Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones

Magnus Rueping; Vilas B. Phapale

doi:10.1039/c1gc15764g

Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones

Magnus Rueping^*, Vilas B. Phapale

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

The [IrCl(cod)]₂ catalyzed α-alkylation of substituted acetophenones with solketal followed by reduction and iron mediated cyclization provides 2,5-disubstituted tetrahydrofurans.

Original language	English (US)
Pages (from-to)	55-57
Number of pages	3
Journal	Green Chemistry
Volume	14
Issue number	1
DOIs	https://doi.org/10.1039/c1gc15764g
State	Published - Jan 2012
Externally published	Yes

ASJC Scopus subject areas

Environmental Chemistry
Pollution

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@article{04c86b3d1eea4ef188e11991e25daa51,

title = "Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones",

abstract = "The [IrCl(cod)]2 catalyzed α-alkylation of substituted acetophenones with solketal followed by reduction and iron mediated cyclization provides 2,5-disubstituted tetrahydrofurans.",

author = "Magnus Rueping and Phapale, {Vilas B.}",

year = "2012",

month = jan,

doi = "10.1039/c1gc15764g",

language = "English (US)",

volume = "14",

pages = "55--57",

journal = "Green Chemistry",

issn = "1463-9262",

publisher = "Royal Society of Chemistry",

number = "1",

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T1 - Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones

AU - Rueping, Magnus

AU - Phapale, Vilas B.

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Y1 - 2012/1

N2 - The [IrCl(cod)]2 catalyzed α-alkylation of substituted acetophenones with solketal followed by reduction and iron mediated cyclization provides 2,5-disubstituted tetrahydrofurans.

AB - The [IrCl(cod)]2 catalyzed α-alkylation of substituted acetophenones with solketal followed by reduction and iron mediated cyclization provides 2,5-disubstituted tetrahydrofurans.

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U2 - 10.1039/c1gc15764g

DO - 10.1039/c1gc15764g

M3 - Article

AN - SCOPUS:84857173928

SN - 1463-9262

VL - 14

SP - 55

EP - 57

JO - Green Chemistry

JF - Green Chemistry

IS - 1

ER -

Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones

Abstract

ASJC Scopus subject areas

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