Breast Microwave Imaging (BMI) has emerged as a competitive and potentially disruptive alternative to conventional breast cancer screening techniques owing to its desirable features and improved detection rate. In this paper, we apply various artificial intelligence, and deep learning approaches for automatic breast tumor detection, classification and localization in an open-source experimental BreastCare dataset obtained using our pre-clinical, portable and cost-effective BMI system. We compare the effectiveness of various cutting-edge machine-learning detection algorithms to assess the usefulness of the obtained data-set. Also, we present a deep learning framework that outperforms state-of-the-art microwave imaging methods and ML algorithms for tumor detection, localization, and characterization. The proposed framework gives promising results using our BMI system's measured reflection coefficients (S11). This work shows the potential advantages of applying cutting-edge deep learning algorithms in practical BMI systems.