Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Polymer-Supported Chiral Amino Alcohols. Evidence for a Two Zinc Species Mechanism

Shinichi Itsuno; Jean M.J. Frechet

doi:10.1021/jo00227a043

Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Polymer-Supported Chiral Amino Alcohols. Evidence for a Two Zinc Species Mechanism

Shinichi Itsuno, Jean M.J. Frechet

Research output: Contribution to journal › Letter › peer-review

144 Scopus citations

Abstract

Polymer-bound chiral amino alcohols (in particular, (dialkylamino)isoborneol) are excellent heterogeneous recyclable catalysts in the enantioselective alkylation of aromatic aldehydes with dialkylzinc.

Original language	English (US)
Pages (from-to)	4140-4142
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	52
Issue number	18
DOIs	https://doi.org/10.1021/jo00227a043
State	Published - Sep 1 1987
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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@article{534a520d0256407a8a9e7b355cf5fba8,

title = "Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Polymer-Supported Chiral Amino Alcohols. Evidence for a Two Zinc Species Mechanism",

abstract = "Polymer-bound chiral amino alcohols (in particular, (dialkylamino)isoborneol) are excellent heterogeneous recyclable catalysts in the enantioselective alkylation of aromatic aldehydes with dialkylzinc.",

author = "Shinichi Itsuno and Frechet, {Jean M.J.}",

year = "1987",

month = sep,

day = "1",

doi = "10.1021/jo00227a043",

language = "English (US)",

volume = "52",

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journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Polymer-Supported Chiral Amino Alcohols. Evidence for a Two Zinc Species Mechanism

AU - Itsuno, Shinichi

AU - Frechet, Jean M.J.

PY - 1987/9/1

Y1 - 1987/9/1

N2 - Polymer-bound chiral amino alcohols (in particular, (dialkylamino)isoborneol) are excellent heterogeneous recyclable catalysts in the enantioselective alkylation of aromatic aldehydes with dialkylzinc.

AB - Polymer-bound chiral amino alcohols (in particular, (dialkylamino)isoborneol) are excellent heterogeneous recyclable catalysts in the enantioselective alkylation of aromatic aldehydes with dialkylzinc.

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U2 - 10.1021/jo00227a043

DO - 10.1021/jo00227a043

M3 - Letter

AN - SCOPUS:33845282255

SN - 0022-3263

VL - 52

SP - 4140

EP - 4142

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 18

ER -

Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Polymer-Supported Chiral Amino Alcohols. Evidence for a Two Zinc Species Mechanism

Abstract

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