TY - JOUR
T1 - Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution
AU - Geering, Andrew D.W.
AU - Maumus, Florian
AU - Copetti, Dario
AU - Choisne, Nathalie
AU - Zwickl, Derrick J.
AU - Zytnicki, Matthias
AU - McTaggart, Alistair R.
AU - Scalabrin, Simone
AU - Vezzulli, Silvia
AU - Wing, Rod A.
AU - Quesneville, Hadi
AU - Teycheney, Pierre Yves
N1 - Generated from Scopus record by KAUST IRTS on 2019-11-20
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The extent and importance of endogenous viral elements have been extensively described in animals but are much less well understood in plants. Here we describe a new genus of Caulimoviridae called € Florendovirus €, members of which have colonized the genomes of a large diversity of flowering plants, sometimes at very high copy numbers (>0.5% total genome content). The genome invasion of Oryza is dated to over 1.8 million years ago (MYA) but phylogeographic evidence points to an even older age of 20-34 MYA for this virus group. Some appear to have had a bipartite genome organization, a unique characteristic among viral retroelements. In Vitis vinifera, 9% of the endogenous florendovirus loci are located within introns and therefore may influence host gene expression. The frequent colocation of endogenous florendovirus loci with TA simple sequence repeats, which are associated with chromosome fragility, suggests sequence capture during repair of double-stranded DNA breaks.
AB - The extent and importance of endogenous viral elements have been extensively described in animals but are much less well understood in plants. Here we describe a new genus of Caulimoviridae called € Florendovirus €, members of which have colonized the genomes of a large diversity of flowering plants, sometimes at very high copy numbers (>0.5% total genome content). The genome invasion of Oryza is dated to over 1.8 million years ago (MYA) but phylogeographic evidence points to an even older age of 20-34 MYA for this virus group. Some appear to have had a bipartite genome organization, a unique characteristic among viral retroelements. In Vitis vinifera, 9% of the endogenous florendovirus loci are located within introns and therefore may influence host gene expression. The frequent colocation of endogenous florendovirus loci with TA simple sequence repeats, which are associated with chromosome fragility, suggests sequence capture during repair of double-stranded DNA breaks.
UR - http://www.nature.com/articles/ncomms6269
UR - http://www.scopus.com/inward/record.url?scp=84923340251&partnerID=8YFLogxK
U2 - 10.1038/ncomms6269
DO - 10.1038/ncomms6269
M3 - Article
SN - 2041-1723
VL - 5
JO - Nature Communications
JF - Nature Communications
ER -