TY - JOUR
T1 - Energy phase shift as mechanism for catalysis
AU - Beke-Somfai, Tamás
AU - Feng, Bobo
AU - Nordén, Bengt
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Grants from KAUST and ERC are gratefully acknowledged.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.
PY - 2012/5
Y1 - 2012/5
N2 - Catalysts are agents that by binding reactant molecules lower the energy barriers to chemical reaction. After reaction the catalyst is regenerated, its unbinding energy recruited from the environment, which is associated with an inevitable loss of energy. We show that combining several catalytic sites to become energetically and temporally phase-shifted relative to each other provides a possibility to sustain the overall reaction by internal 'energy recycling', bypassing the need for thermal activation, and in principle allowing the system to work adiabatically. Using an analytical model for superimposed, phase-shifted potentials of F 1-ATP synthase provides a description integrating main characteristics of this rotary enzyme complex. © 2012 Elsevier B.V. All rights reserved.
AB - Catalysts are agents that by binding reactant molecules lower the energy barriers to chemical reaction. After reaction the catalyst is regenerated, its unbinding energy recruited from the environment, which is associated with an inevitable loss of energy. We show that combining several catalytic sites to become energetically and temporally phase-shifted relative to each other provides a possibility to sustain the overall reaction by internal 'energy recycling', bypassing the need for thermal activation, and in principle allowing the system to work adiabatically. Using an analytical model for superimposed, phase-shifted potentials of F 1-ATP synthase provides a description integrating main characteristics of this rotary enzyme complex. © 2012 Elsevier B.V. All rights reserved.
UR - http://hdl.handle.net/10754/598169
UR - https://linkinghub.elsevier.com/retrieve/pii/S0009261412003508
UR - http://www.scopus.com/inward/record.url?scp=84860264461&partnerID=8YFLogxK
U2 - 10.1016/j.cplett.2012.03.039
DO - 10.1016/j.cplett.2012.03.039
M3 - Article
SN - 0009-2614
VL - 535
SP - 169
EP - 172
JO - Chemical Physics Letters
JF - Chemical Physics Letters
ER -