TY - JOUR
T1 - Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
AU - Zaidi, Syed Shan-e-Ali
AU - Mahas, Ahmed
AU - Vanderschuren, Hervé
AU - Mahfouz, Magdy M.
N1 - KAUST Repository Item: Exported on 2020-12-02
Acknowledged KAUST grant number(s): OSR-2015-CRG4-2647
Acknowledgements: We wish to thank members of the Laboratory for Genome Engineering and Synthetic Biology at King Abdullah University of Science and Technology for helpful discussions and comments on the manuscript.
PY - 2020/11/30
Y1 - 2020/11/30
N2 - AbstractTo meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistance traits. With precise genome engineering and transgene-free applications, CRISPR is expected to resolve the major challenges to crop improvement. Here, we discuss the latest developments in CRISPR technologies for engineering resistance to viruses, bacteria, fungi, and pests. We conclude by highlighting current concerns and gaps in technology, as well as outstanding questions for future research.
AB - AbstractTo meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistance traits. With precise genome engineering and transgene-free applications, CRISPR is expected to resolve the major challenges to crop improvement. Here, we discuss the latest developments in CRISPR technologies for engineering resistance to viruses, bacteria, fungi, and pests. We conclude by highlighting current concerns and gaps in technology, as well as outstanding questions for future research.
UR - http://hdl.handle.net/10754/666173
UR - https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02204-y
U2 - 10.1186/s13059-020-02204-y
DO - 10.1186/s13059-020-02204-y
M3 - Article
C2 - 33256828
SN - 1474-760X
VL - 21
JO - Genome biology
JF - Genome biology
IS - 1
ER -
