Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm

XD Ye; S Al-Babili; A Kloti; J Zhang; P Lucca; P Beyer; Ingo Potrykus

Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm

XD Ye, S Al-Babili, A Kloti, J Zhang, P Lucca, P Beyer^*, Ingo Potrykus

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1869 Scopus citations

Abstract

Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, Lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.

Original language	English
Pages (from-to)	303-305
Number of pages	3
Journal	Science
Volume	287
Issue number	5451
State	Published - Jan 14 2000
Externally published	Yes

Keywords

VITAMIN-A-DEFICIENCY
NARCISSUS-PSEUDONARCISSUS
FUNCTIONAL EXPRESSION
PLANT TRANSFORMATION
PHYTOENE SYNTHASE
VECTORS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm",

abstract = "Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, Lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.",

keywords = "VITAMIN-A-DEFICIENCY, NARCISSUS-PSEUDONARCISSUS, FUNCTIONAL EXPRESSION, PLANT TRANSFORMATION, PHYTOENE SYNTHASE, VECTORS",

author = "XD Ye and S Al-Babili and A Kloti and J Zhang and P Lucca and P Beyer and Ingo Potrykus",

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TY - JOUR

T1 - Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm

AU - Ye, XD

AU - Al-Babili, S

AU - Kloti, A

AU - Zhang, J

AU - Lucca, P

AU - Beyer, P

AU - Potrykus, Ingo

PY - 2000/1/14

Y1 - 2000/1/14

N2 - Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, Lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.

AB - Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, Lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.

KW - VITAMIN-A-DEFICIENCY

KW - NARCISSUS-PSEUDONARCISSUS

KW - FUNCTIONAL EXPRESSION

KW - PLANT TRANSFORMATION

KW - PHYTOENE SYNTHASE

KW - VECTORS

M3 - Article

SN - 0036-8075

VL - 287

SP - 303

EP - 305

JO - Science

JF - Science

IS - 5451

ER -

Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm

Abstract

Keywords

UN SDGs

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