TY - JOUR
T1 - Fabrication of 3D-Printed Contact Lenses and Their Potential as Color Blindness Ocular Aids
AU - Hittini, Saba
AU - Salih, Ahmed E.
AU - Alam, Fahad
AU - Shanti, Aya
AU - Lee, Sungmun
AU - Polychronopoulou, Kyriaki
AU - AlSafar, Habiba
AU - Almaskari, Fahad
AU - Butt, Haider
N1 - Generated from Scopus record by KAUST IRTS on 2023-09-23
PY - 2023/5/1
Y1 - 2023/5/1
N2 - Color blindness or color vision deficiency (CVD) is a congenital ocular deficiency that hampers patients’ daily life activities. CVD patients rely mostly on using wearable visual aids that enhance color distinction by blocking problematic wavelengths of light. Contributing to that, this study examines the fabrication of 3D-printed colored contact lens for color blindness management. A vat photopolymerization based 3D printing technology is utilized to fabricate the contact lenses for CVD patients. An in-house prepared resin is mixed with a low-cost colored ink to attain the desired blocking range (520–580 nm). The fabricated lens blocks more than 50% of light at the problematic wavelengths, along with exhibiting minimal leakage when stored and examined in water and contact lens storage solution. Average contact angle and water content values are 48° and 56%, respectively. Mechanical properties demonstrate the physical adequacy of the contact lens. The CVD filtering efficacy of the tinted contact lens and its potential as a CVD wearable is evaluated by comparing its optical performance with that of commercial products. Finally, cytotoxicity analysis of the lens to dermal fibroblast cells reveals the biocompatibility of the lens as the cell viability remains greater than 75% after 24 h.
AB - Color blindness or color vision deficiency (CVD) is a congenital ocular deficiency that hampers patients’ daily life activities. CVD patients rely mostly on using wearable visual aids that enhance color distinction by blocking problematic wavelengths of light. Contributing to that, this study examines the fabrication of 3D-printed colored contact lens for color blindness management. A vat photopolymerization based 3D printing technology is utilized to fabricate the contact lenses for CVD patients. An in-house prepared resin is mixed with a low-cost colored ink to attain the desired blocking range (520–580 nm). The fabricated lens blocks more than 50% of light at the problematic wavelengths, along with exhibiting minimal leakage when stored and examined in water and contact lens storage solution. Average contact angle and water content values are 48° and 56%, respectively. Mechanical properties demonstrate the physical adequacy of the contact lens. The CVD filtering efficacy of the tinted contact lens and its potential as a CVD wearable is evaluated by comparing its optical performance with that of commercial products. Finally, cytotoxicity analysis of the lens to dermal fibroblast cells reveals the biocompatibility of the lens as the cell viability remains greater than 75% after 24 h.
UR - https://onlinelibrary.wiley.com/doi/10.1002/mame.202200601
UR - http://www.scopus.com/inward/record.url?scp=85150954654&partnerID=8YFLogxK
U2 - 10.1002/mame.202200601
DO - 10.1002/mame.202200601
M3 - Article
SN - 1438-7492
VL - 308
JO - Macromolecular Materials and Engineering
JF - Macromolecular Materials and Engineering
IS - 5
ER -