Abstract
The principal objective of this work is to design a novel and improved membranous support for electrochemical sensing of cholesterol by the application of CNT. The present work is based on potentiometric sensing of cholesterol through a cellulose acetate membranous support embedded with a single walled carbon nanotubes (SWNT). Cholesterol Oxidase (ChOx) has been immobilized on the carbon nanotubes mixed cellulose acetate membrane (CA-CNT). Scanning electron microscopic images have shown that cholesterol oxidase is uniformly immobilized over the CA-CNT membrane. The electrocatalytic responses of ChOx/CA-CNT were investigated with various concentration of cholesterol ranging from 10-3 M to 10-8 M. Compared with ChOx/CA, the ChOx/CA-CNT has better electrocatalytic response to cholesterol. This sensor shows excellent performance with high sensitivity, with a linear range of 10-3 M to 10-8 M, and a detection limit of 10-8 M.
Original language | English (US) |
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Pages (from-to) | 102-108 |
Number of pages | 7 |
Journal | Sensor Letters |
Volume | 14 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2016 |
Externally published | Yes |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electrical and Electronic Engineering