First heterogeneous ligand- and salt-free larock indole Synthesis

Nelly Batail, Anissa Bendjeriou-Sedjerari, Thierry Lomberget, Roland Barrett, Véronique Dufaud*, Laurent Djakovitch

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations


    A new ligand- and salt-free procedure using heterogeneous palladium catalysts for the Larock indole and benzofuran synthesis is reported. After optimisation of the reaction conditions, good to high isolated yields have been achieved for a variety of structures. Recycling studies have shown that the palladium catalysts can be readily recovered and reused. Reactions and recovery of the palladium catalysts can be carried out in the presence of air, without any particular precaution.

    Original languageEnglish (US)
    Pages (from-to)2055-2062
    Number of pages8
    JournalAdvanced Synthesis and Catalysis
    Issue number13
    StatePublished - Jan 1 2009


    • Benzofurans
    • Heterogeneous catalysis
    • Indoles
    • Larock synthesis
    • Palladium catalysts

    ASJC Scopus subject areas

    • Catalysis
    • Organic Chemistry


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